In the event of radiation poisoning, the victim loses Endurance, not hit points. The rate of loss depends on the length of time exposed, and the intensity of exposure. Generally, radiation doses are measured in R.E.M.s, (in the World of Gaianar, this stands for Radiation Equivalent to Man). Fatal radiation exposure begins at 250 R.E.M.s. The table below displays the rate at which Endurance is lost. At each save interval, a successful save versus poison indicated that Endurance is not lost during that particular interval; failure indicates that one point is lost permanently.
| Table: Endurance Loss From Radiation Poisoning | |
| R.E.M.s | Poison Save Interval |
| 250 to 374 | Every year |
| 375 to 499 | Every three months |
| 500 to 699 | Every month |
| 700 to 849 | Every week |
| 850 to 949 | Every day |
| 950 to 979 | Every hour |
| 980 to 994 | Every turn |
| 995 to 1000 | Every round |
| Above 1000 | Instant death |
An application of Imbue With Life Energy, or equivalent will halt the loss of Endurance. A Complete Regeneration that immediately follows a Remove Poison will also halt the progression. Only a Total Restoration will fully restore a character damaged by radiation poisoning.
If the irradiated character is the recipient of a Remove Poison one per day for three consecutive months the Endurance loss will also be halted (if the character lives that long, of course.) Additionally, the severity of radiation poisoning can be dropped by two levels by a physician of no less than eight intensities of combined Healing, Advanced Medical, Chemistry, and/or Herbalism.
If the character dies of radiation poisoning, he or she cannot be raised from the dead unless a Remove Poison is first invoked over the body. Once the Raise Dead has been invoked, Imbue With Life Energy must follow, or else the victim is still irradiated, albeit at half the number of R.E.M.s.
A character's body will also dissipate radiation poisoning at the rate of 5 R.E.M's per point of Constitution per year (divide this rate up evenly per month).
Once a person has received more than 250 R.E.M., natural healing will forever occur at a slower rate. This is due to permanent damage done at the capillary level (in real life, people who have undergone radiation treatment for cancer often have problems with non-healing wounds later in life, due to the fact that capillary damage reduces the flow of blood (and therefore oxygen) to the extremities.) A person who has been damaged by radiation (above 250 R.E.M.) will recover hit points at half his normal rate until the radiation level in his system is below dangerous levels.
A Complete Regeneration or similar power will allow the recipient to heal at the normal rate, rather than the reduced rate. This is because the Complete Regeneration power can repair damaged capillaries.